Hypothesis on the molecular basis of the antifungal activity of N-substituted imidazoles and triazoles.
نویسندگان
چکیده
known as denmert) caused total loss of its fungicidal activity towards Sphaerotheca fuliginea and Monilinia fmctigena. These workers suggested that the co-ordination of the heterocyclic meta-nitrogen atom of buthiobate to a cationic receptor site may be important for its fungicidal activity. The cationic receptor site mentioned would appear to be the Fez+ of the cytochrome P-450 catalysing step 1 of the sterol 14-demethylation sequence.
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ورودعنوان ژورنال:
- Biochemical Society transactions
دوره 11 6 شماره
صفحات -
تاریخ انتشار 1983